Exploring the Potential of Gold Nanoparticles in Nanomedicine: A Comprehensive Analysis of Benefits and Limitations

Kamyar Shameli; Zahra Izadiyan; Pooneh Kia; Hemra Hamrayev; Hossein Jahangirian; Aras Kartouzian; Emad Abbas Jaffar Al-Mulla; Hassan Moeini

doi:10.37934/jrnn.11.1.115

Authors

Kamyar Shameli Institute of Virology, Department of Medicine, Technical University of Munich, Munich, 81675, Germany
Zahra Izadiyan Department of Chemistry, Faculty of Science, Universiti Malaya, Kuala Lumpur, 50603, Malaysia
Pooneh Kia Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
Hemra Hamrayev Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, Kuala Lumpur, Malaysia
Hossein Jahangirian Green Nano Biotech, LLC, Quincy, 02169 MA, United States of America
Aras Kartouzian Catalysis Research Center and School of Natural Science, Technical University of Munich, Garching, Germany
Emad Abbas Jaffar Al-Mulla College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, 54001 An-Najaf, Iraq
Hassan Moeini Iguana Biotechnology GmbH, 80331 Munich, Germany

DOI:

https://doi.org/10.37934/jrnn.11.1.115

Keywords:

Gold nanoparticles, Nanomedicine, Physicochemical characteristics, Biocompatibility, Toxicity

Abstract

This paper delves into the utilization of gold nanoparticles (Au-NPs) in nanomedicine, examining both their advantageous properties and associated drawbacks. Au-NPs have gained significant attention in biomedical applications owing to their unique physicochemical characteristics, such as biocompatibility, tunable optical properties, and facile surface functionalization. These attributes render Au-NPs promising candidates for various therapeutic and diagnostic purposes in nanomedicine. However, their implementation also presents challenges, including concerns regarding toxicity, stability, and scalability. This review offers a critical assessment of the advantages and disadvantages of employing Au-NPs in nanomedicine, aiming to provide insights for researchers and clinicians navigating the complexities of nanoparticle-based therapies.