Curcumin Extract Loaded with Chitosan Nanocomposite for Cancer Treatment

Abstract

Cancer has become the root of problems in this era especially during this modern medicine time and because of that anticancer treatment had been developed to cure the patient suffering from this disease and for that an adoption of curcumin extract becomes a great deal of interest because of its anticancer properties. A recent study had been done aimed at determining the potential anticancer properties by chitosan in nanoparticle form. Furthermore, curcumin's weak water solubility enables it to accumulate in high concentrations, lowering its permeability to the cell. Curcumin is reduced via a variety of methods. With improving medicinal and research capabilities, nowadays the nano-pharmaceutics became an important field of science to develop an improve efficacy of different drugs specifically that target cancer diseases. In the present review, we focus on the plant extract of curcumin from Curcuma Longa plant and chitosan which derived from chitin in the exoskeletons of crustaceans which then be encapsulated into a nanocarrier formulation that can overcome this cancer. Thus, curcumin's potential preventative and therapeutic applications, as well as several forms of bio-nanocarriers that can be employed to effectively deliver curcumin to various target areas, will be reviewed.